Depends on the firearms.
For my semiautomatic pistols (Glocks, Sig) and semiautomatic rifles (Bushmaster XM15, L1A1), personal defense first. Target shooting second. Occasionally, I'll do some handgun hunting with the 10 mm, though.
For my bolt action rifle (Remington 700), hunting first, target shooting second. I really don't consider this a defensive weapon, unless my attacker is going to be firing at me from 500 yards.
For my Remington 1100 and Remingtin 870 shotguns, personal defense comes first. Both are stoked with full magazines of 12 gauge Federal Tactical 00 buckshot. I'll occasionally do some skeet shooting with the 1100 (target loads), and some hunting with the 870 (slugs).
Once in a while, I'll use a handgun, rifle, and shotgun in 3 gun competitions.