Going through this, I was thinking of permanent, irreversible changes to the brain. Not 'wiring/logic' changes that can and do change on a regular basis. Not sure if that makes sense to you, but are you talking about temporal changes or permanent changes? I am having a hard time imagining an emotional trauma making a permanent, physical change. It would be fascinating to see that mapped out.Yep. There's plenty of evidence that trauma - both mental and physical - can cause epigenetic changes. My memory on the topic is hazy, but I think those can lead to genetic changes over time.