Sometimes I carry with a round chambered, sometimes I don't. Quite comfortable both ways. Always qualify both hands as well, been doing that since the eighties. That came in handy yesterday as I had to clear some defunct storage areas that had no lights and strange twist and turns. (a few I had never been in before) Sure wakes you up in a hurry on an otherwise peaceful day. Afterwards I had a triple expresso - just to bring my heart rate down.